disease

disease is a Noun

Definition:

[1] Lack of ease; uneasiness; trouble; vexation; disquiet. [Obs.] So all that night they passed in great disease. Spenser. To shield thee from diseases of the world. Shak.

[2] An alteration in the state of the body or of some of its organs, interrupting or disturbing the performance of the vital functions, and causing or threatening pain and weakness; malady; affection; illness; sickness; disorder; -- applied figuratively to the mind, to the moral character and habits, to institutions, the state, etc. Diseases desperate grown, By desperate appliances are relieved. Shak. The instability, injustice, and confusion introduced into the public counsels have, in truth, been the mortal diseases under which popular governments have every where perished. Madison. Disease germ. See under Germ.